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Research Opportunity: DNA-Protein Epigenetic Chemistry Engineering (D-PECHE)

Key dates

Posted
May 18, 2026
Response deadline
Jun 24, 2026, 4:00 PM UTC
Archive date
—
Archive type
autocustom

Classification

Notice type
Special Notice
Base type
Special Notice
Set-aside
—
Set-aside code
—
PSC
AC11

NAICS

Issuing office

Department
DEPT OF DEFENSE
Sub-tier
DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)
Office
DEF ADVANCED RESEARCH PROJECTS AGCY
Office code
097.97AE.HR0011
Organization type
OFFICE
Office address
ARLINGTON, VA, 222032114, USA

Contacts

Description

UPDATE: The purpose of Amendment 1 to DARPA-SN-26-67, the DNA-Protein Epigenetic Chemistry Engineering (D-PECHE) Special Notice (SN), is to clarify submission instructions and deadlines. The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative proposals to demonstrate proof-of-concept for novel mechanisms for writing and erasing epigenetic base modifications in DNA. Mechanisms capable of modifying the epigenome offer new opportunities to control DNA-protein interactions and to study the functions and applications of rare or novel epigenetic modifications. This research opportunity will result in demonstrations of novel technologies to modify nucleic acids in vitro.

Attachments (2)

Other notices in this solicitation

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Metadata

Notice ID
553632b7e7fd49a7884a1c32f8a611c5
Full path
DEPT OF DEFENSE.DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA).DEF ADVANCED RESEARCH PROJECTS AGCY
Office code
097.97AE.HR0011
Ingested
May 19, 2026
Updated
Jun 25, 2026