Research and Development in Biotechnology (except Nanobiotechnology) government contracts, bids & RFPs
NAICS 541714 · 43 open opportunities · 24 awards on record
This U.S. industry comprises establishments primarily engaged in conducting biotechnology (except nanobiotechnology) research and experimental development. Biotechnology (except nanobiotechnology) research and experimental development involves the study of the use of microorganisms and cellular and biomolecular processes to develop or alter living or non-living materials. This research and development in biotechnology (except nanobiotechnology) may result in development of new biotechnology (except nanobiotechnology) processes or in prototypes of new or genetically-altered products that may be reproduced, utilized, or implemented by various industries. Illustrative Examples: Cloning research and experimental development laboratories DNA technologies (e.g., microarrays) research and experimental development laboratories Nucleic acid chemistry research and experimental development laboratories Protein engineering research and experimental development laboratories Recombinant DNA research and experimental development laboratories Cross-References. Establishments primarily engaged in--
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- U.S. industry541714 Research and Development in Biotechnology (except Nanobiotechnology)
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By the numbers
- Avg reported value
- $74M
- Median reported value
- $1M
- Total reported value
- $2B
- Awards on record
- 24
- Companies
- 8
SAM.gov award-notice values may represent contract ceilings rather than obligated spending.
3 of 43 open Research and Development in Biotechnology (except Nanobiotechnology) opportunities (7%) are set aside for small or disadvantaged businesses.
Research and Development in Biotechnology (except Nanobiotechnology) contract activity
A current snapshot based on 15 of 43 open listings shown on this page. Counts update with the directory.
- Federal (SAM.gov)15
Deadline outlook
- Next 30 days
- 13
- Later
- 2
- Open / rolling
- 0
Most represented buyers
- NATIONAL INSTITUTES OF HEALTH6
- DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)4
- DEFENSE HEALTH AGENCY (DHA)2
- DEPT OF THE NAVY1
- Other2
11 of the listings shown were posted in the last 30 days. Federal (SAM.gov) contributes the largest share (15). NATIONAL INSTITUTES OF HEALTH is the most represented buyer in this snapshot.
Open opportunities
- SURPASS Webinar and Proposers' Day InformationHEALTH AND HUMAN SERVICES, DEPARTMENT OF / NATIONAL INSTITUTES OF HEALTH
1 Special Notice (SN) ARPA-H-SN-26-164 Webinar and Proposers’ Day Announcement for Simulation-augmented, Real-time Platform Adaptive Seamless Trials (SURPASS) I. KEY INFORMATION Table 1. Key Information Informational Webinar (Online) October 15, 2026, from 12:00 PM to 1:00 PM ET Proposers’ Day (Hybrid) Day 1: November 6, 2026, from 9:00 AM to 5:00 PM ET Hybrid: in-person and virtual Day 2: November 9, 2026, from 9:00 AM to 12:00 PM ET Virtual Proposer’s Day Location Day 1: Washington, DC and…
MoreDue Oct 13, 2026Posted Sep 30, 2026 - UNifying Imaging with QUantum Entanglement (UNIQUE) Proposers' DayHEALTH AND HUMAN SERVICES, DEPARTMENT OF / NATIONAL INSTITUTES OF HEALTH
This Special Notice (SN) alerts the scientific community to a newly approved ARPA-H program and notifies potential proposers of an associated Proposers’ Day. See attached UNIQUE-SN-ARPA-H-SN-26-162 for further details. A Lightning Talk Template is also provided for convenience. The exact location of the Proposers' Day is TBD and this SN will be amended with the location as soon as it is finalized.
MoreDue Oct 13, 2026Posted Sep 16, 2026 - UNifying Imaging with QUantum Entanglement (UNIQUE) Proposers' DayHEALTH AND HUMAN SERVICES, DEPARTMENT OF / NATIONAL INSTITUTES OF HEALTH
Amendment 01: The Special Notice has been amended to specify that the Proposers Day will take place at 8:30am ET on October 16th, 2026, at the Executive Conference Center (ECC) located at 4075 Wilson Blvd, Suite 300, Arlington, VA 22203. This Special Notice (SN) alerts the scientific community to a newly approved ARPA-H program and notifies potential proposers of an associated Proposers’ Day. See attached UNIQUE-SN-ARPA-H-SN-26-162 for further details. A Lightning Talk Template is also…
MoreDue Oct 14, 2026Posted Sep 24, 2026 - Sepsis Research Blood Sample Collection ServicesDEPT OF DEFENSE / DEFENSE HEALTH AGENCY (DHA)
Notice of Intent (NOI) to Sole Source Title: Sepsis Research Blood Sample Collection Services Requiring Activity: Walter Reed Army Institute of Research (WRAIR), Integrative Systems Biology (ISB) Branch Related Notice: HT942523P0084 Product Service Code (PSC): AN11 - HEALTH R&D SERVICES; HEALTH CARE SERVICES; BASIC RESEARCH North American Industry Classification System (NAICS) Code: 541714 - Research and Development in Biotechnology (except Nanobiotechnology) Small Business Size Standard: 1000…
MoreDue Oct 15, 2026Posted Sep 1, 2026 - Request for Information (RFI) on Identifying Basic Research Challenges to Accelerate United States Biotechnology LeadershipENERGY, DEPARTMENT OF
DOE seeks input on critical basic research challenges, bottlenecks, and missing capabilities needed to transition from descriptive biology to predictive biosystems design. This RFI solicits perspectives on advancing foundational science across biomolecules, cells, microbiomes, and plants to accelerate the production of bio-advantaged fuels, chemicals, and materials. Feedback is specifically requested on fundamental biodesign goals, high-priority biotechnology application areas, and effective…
MoreDue Oct 15, 2026Posted Sep 24, 2026 - Protein ENGineering (PENG)DEPT OF DEFENSE / DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)
The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative proposals for the development of a multifunctional, target-agnostic platform for precise, programmable editing of endogenous proteins. The goal of the Protein ENGineering (PENG) program is to transition proteome engineering from a collection of isolated, bespoke tools into a universal, software-defined discipline. The PENG program will establish a comprehensive, integrated platform composed of modular targeting,…
MoreDue Oct 19, 2026Posted Aug 21, 2026 - Protein ENGineering (PENG)DEPT OF DEFENSE / DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)
The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative proposals for the development of a multifunctional, target-agnostic platform for precise, programmable editing of endogenous proteins. The goal of the Protein ENGineering (PENG) program is to transition proteome engineering from a collection of isolated, bespoke tools into a universal, software-defined discipline. The PENG program will establish a comprehensive, integrated platform composed of modular targeting,…
MoreDue Oct 19, 2026Posted Aug 7, 2026 - Biobanking, Laboratory Analytics, and Associated Informatics Services for NIH BiorepositoriesHEALTH AND HUMAN SERVICES, DEPARTMENT OF / NATIONAL INSTITUTES OF HEALTH
SOURCES SOUGHT NOTICE – No. 75N98026R00175 Title: Biobanking, Laboratory Analytics, and Associated Informatics Services for NIH Biorepositories Agency: National Institutes of Health (NIH) Description This is a SOURCES SOUGHT NOTICE. This is NOT a solicitation for proposals, proposal of abstracts or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified business sources and (2) whether commercial sources and services are…
MoreDue Oct 20, 2026Posted Sep 28, 2026 - Biobanking, Laboratory Analytics, and Associated Informatics Services for NIH BiorepositoriesHEALTH AND HUMAN SERVICES, DEPARTMENT OF / NATIONAL INSTITUTES OF HEALTH
SOURCES SOUGHT NOTICE – No. 75N98026R00175 Title: Biobanking, Laboratory Analytics, and Associated Informatics Services for NIH Biorepositories Agency: National Institutes of Health (NIH) Description This is a SOURCES SOUGHT NOTICE. This is NOT a solicitation for proposals, proposal of abstracts or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified business sources and (2) whether commercial sources and services are…
MoreDue Oct 20, 2026Posted Sep 28, 2026 - Due Oct 20, 2026Posted Oct 1, 2026
- NAWCWD Broad Agency AnnouncementDEPT OF DEFENSE / DEPT OF THE NAVY
This publication constitutes a Broad Agency Announcement (BAA) as contemplated in Federal Acquisition Regulation (FAR) 6.102(d)(2) and 35.016, and the Department of Defense Grants and Agreements Regulations (DoDGARS) 22.315(a). Pursuant to FAR 6.102(d)(2)(i) a formal Request for Proposal (RFP), solicitation, and/or additional information regarding this announcement will not be issued. The Naval Air Warfare Center Weapons Division (NAWCWD) will not issue paper copies of this announcement.…
MoreDue Oct 30, 2026Posted Dec 30, 2025 - Due Nov 2, 2026Posted Sep 18, 2026
- Due Nov 5, 2026Posted Oct 8, 2026
- FirefoxDEPT OF DEFENSE / DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)
The Defense Advanced Research Projects Agency (DARPA) has developed a non-invasive coherent optical system capable of recording neural signals in humans. To expand this foundational technology and enable the development of revolutionary, non-invasive brain-computer interfaces (BCIs), DARPA's Firefox program is soliciting approaches to overcome key technological hurdles: 1) development of components enabling dynamic rastering/scanning of the incoming coherent optical signal to target multiple…
MoreDue Nov 9, 2026Posted Sep 16, 2026 - Request for Proposals (RFP) - BARDA Vaccine Medical Countermeasures for Pandemic Influenza Preparedness & ResponseHEALTH AND HUMAN SERVICES, DEPARTMENT OF / OFFICE OF ASSISTANT SECRETARY FOR PREPAREDNESS AND RESPONSE
BARDA seeks Contractor(s) to support the continuation of the Vaccine Medical Counermeasures (MCM's) for Pandemic Influenza Preparedness and Response Program. Contractors will furnish all the necessary services, qualified personnel, materials, supplies, equipment and facilities (U.S. facilities preferred) not otherwise provided by the USG as needed to provide MCMs, such as vaccines, antigens, and adjuvants, for pandemic preparedness and response or as required in response to a public health…
MoreDue Nov 20, 2026Posted Sep 11, 2026
Top awardees
| Awardee | # Awards | Reported Value | Last Award |
|---|---|---|---|
| ALBERT B. SABIN VACCINE INSTITUTE, INC. (THE) UEI H5E8NU6N2HZ5 | 1 | $1B | May 5, 2026 |
| Flosonics Medical LLC Mountain View CA 94040 USA UEI RD81CL8M8EM9 | 1 | $100M | Jun 5, 2026 |
| CHENEGA SERVICES & FEDERAL SOLUTIONS, LLC UEI YN3KSHRHEMM1 | 1 | $72M | May 19, 2026 |
| NATIONAL COLLEGIATE INVENTORS & INNOVATORS ALLIANCE, INC. Hadley MA 01035 USA UEI D5S9JZ1KDP49 | 1 | $1M | Jun 8, 2026 |
| ENGINEERING BIOLOGY RESEARCH CONSORTIUM Emeryville CA 94608 USA UEI M5K1N5ZVSLD5 | 1 | $1M | Jun 8, 2026 |
| ILLUMINA, INC. San Diego CA 92122 USA UEI KMW3CRWNAAF3 | 1 | $273,352 | May 30, 2026 |
| VIRSCIO, INC NEW HAVEN 06511 CTE UEI EYCBWGA47PL5 | 1 | $185,908 | Jun 1, 2026 |
| TWIST BIOSCIENCE CORPORATION San Francisco CA 94080 USA UEI CMN5DM38JLN1 | 1 | $47,450 | Jun 24, 2026 |
Agencies that buy Research and Development in Biotechnology (except Nanobiotechnology)
States with the most open Research and Development in Biotechnology (except Nanobiotechnology) bids
Current open NAICS 541714 opportunities by place of performance.
Frequently asked
Across 24 SAM.gov award notices for NAICS 541714 (Research and Development in Biotechnology (except Nanobiotechnology)), the average reported value is $74M and the median is $1M. SAM.gov award-notice values may represent contract ceilings rather than obligated spending.
8 distinct companies have won awards in NAICS 541714 (Research and Development in Biotechnology (except Nanobiotechnology)).
The agencies awarding the most NAICS 541714 contracts are Department of Defense, Department of Health and Human Services, Department of Veterans Affairs.
Yes — 3 of the 43 currently-open Research and Development in Biotechnology (except Nanobiotechnology) opportunities (7%) are set aside for small or disadvantaged businesses.
The states with the most currently-open NAICS 541714 opportunities are New Mexico, Washington, DC, Maryland.