Research and Development in Biotechnology (except Nanobiotechnology) government contracts, bids & RFPs
NAICS 541714 · 38 open opportunities · 16 awards on record
This U.S. industry comprises establishments primarily engaged in conducting biotechnology (except nanobiotechnology) research and experimental development. Biotechnology (except nanobiotechnology) research and experimental development involves the study of the use of microorganisms and cellular and biomolecular processes to develop or alter living or non-living materials. This research and development in biotechnology (except nanobiotechnology) may result in development of new biotechnology (except nanobiotechnology) processes or in prototypes of new or genetically-altered products that may be reproduced, utilized, or implemented by various industries. Illustrative Examples: Cloning research and experimental development laboratories DNA technologies (e.g., microarrays) research and experimental development laboratories Nucleic acid chemistry research and experimental development laboratories Protein engineering research and experimental development laboratories Recombinant DNA research and experimental development laboratories Cross-References. Establishments primarily engaged in--
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By the numbers
- Avg reported value
- $83M
- Median reported value
- $1M
- Total reported value
- $1B
- Awards on record
- 16
- Companies
- 8
SAM.gov award-notice values may represent contract ceilings rather than obligated spending.
4 of 38 open Research and Development in Biotechnology (except Nanobiotechnology) opportunities (11%) are set aside for small or disadvantaged businesses.
Research and Development in Biotechnology (except Nanobiotechnology) contract activity
A current snapshot based on 15 of 38 open listings shown on this page. Counts update with the directory.
- Federal (SAM.gov)15
Deadline outlook
- Next 30 days
- 13
- Later
- 2
- Open / rolling
- 0
Most represented buyers
- DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)4
- AGRICULTURAL RESEARCH SERVICE3
- NATIONAL AERONAUTICS AND SPACE ADMINISTRATION3
- NATIONAL INSTITUTES OF HEALTH2
- Other3
13 of the listings shown were posted in the last 30 days. Federal (SAM.gov) contributes the largest share (15). DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA) is the most represented buyer in this snapshot.
Open opportunities
- Low-Pass Sequencing of Cotton Accessions - College Station TXAGRICULTURE, DEPARTMENT OF / AGRICULTURAL RESEARCH SERVICE
This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR Part 12. This announcement constitutes the only solicitation. Quotations are being requested and a separate written solicitation will not be issued. Solicitation number 1232SA26Q1144 is issued as a Request for Quotation (RFQ) for Low-Pass Sequencing of Cotton Accessions. This acquisition is not set-aside for small business concerns. The applicable North American Industry Classification…
MoreDue Aug 26, 2026Posted Aug 10, 2026 - Notice of Intent to Award Using Other than Full and Open Competition -Ice Control for Cold Environments (ICE)DEPT OF DEFENSE / DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)
The Defense Advanced Research Projects Agency (DARPA), Contracts Management Office (CMO), on behalf of the Biological Technologies Office (BTO), intends to enter into modifications to award Phase III to existing awards under the Ice Control for Cold Environments (ICE) program to the Michigan Technological University, University of Michigan, and Ginkgo Bioworks, Inc.
MoreDue Aug 26, 2026Posted Aug 11, 2026 - Nanobody against NPR-C for growth disorderHEALTH AND HUMAN SERVICES, DEPARTMENT OF / NATIONAL INSTITUTES OF HEALTH
See attached Word document. Project Title: Nanobody against NPR-C for growth disorder 1. Project Overview 1.1 Background We sought to develop nanobodies (VHH) against human NPR-C with high affinity and specificity for future clinical use. These nanobodies could potentially be further developed into therapeutics for treatment of growth disorders such as achondroplasia. 1.2 Main Objectives - generation of antigens needed for immunization - immunization of Alpaca/Ilama with target antigens…
MoreDue Aug 28, 2026Posted Aug 18, 2026 - Yeast Two-Hybrid (Y2H) Screening ServiceAGRICULTURE, DEPARTMENT OF / AGRICULTURAL RESEARCH SERVICE
This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR Part 12. This announcement constitutes the only solicitation. Quotations are being requested and a separate written solicitation will not be issued. Solicitation number 1232SA26Q1181 is issued as a Request for Quotation (RFQ) for Yeast Two-Hybrid (Y2H) Screening Service for the Robert W. Holley Center for Agriculture and Health. This acquisition is set-aside for small business concerns.…
MoreDue Aug 28, 2026Posted Aug 4, 2026 - Skin commensal sequencingHEALTH AND HUMAN SERVICES, DEPARTMENT OF / NATIONAL INSTITUTES OF HEALTH
General Information Document Type: Presolicitation Synopsis Number: 75N98026Q01038 Posted Date: August 19, 2026 Original Response Date: August 31, 2026 Current Response Date: August 31, 2026 Set Aside: N/A NAICS Code: 541714 Contracting Office Address National Institutes of Health (NIH), Office of the Director (OD) Office of Logistics and Operations (OLAO) Office of Acquisition and Logistics Management (OALM) Hospital and Laboratory Support Division 6701 Rockledge Drive Bethesda, MD 20817…
MoreDue Aug 31, 2026Posted Aug 19, 2026 - Future Program: Intrinsic Market Resilience (IMR)DEPT OF DEFENSE / DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)
The evolution of markets from physical trading floors to interconnected, electronic venues has introduced new speed, transparency, and efficiency, but has also created new attack surfaces and systemic risks. Modern markets, which host trading for everything from equities and bonds to energy and cloud computing resources, can be manipulated in ways unanticipated by their designers. The 2010 United States Equity market "flash crash" and the 2000-2001 California energy crisis demonstrated how…
MoreDue Aug 31, 2026Posted Aug 11, 2026 - Due Sep 1, 2026Posted Aug 25, 2026
- Bridge Contract - Disease Surveillance and Research SupportDEPT OF DEFENSE / DEFENSE HEALTH AGENCY (DHA)
The Defense Health Agency Contracting Activity (DHACA) – R&D Branch 1 intends to negotiate on a 12-month bridge contract on a sole source basis, IAW 10 United States Code 3204(a)(1) as implemented in FAR 6.103-1(c)(2)(ii) to The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., 6720A Rockledge Dr, STE 100, Bethesda, MD 20817, as the only responsible source that can provide the Walter Reed Army Institute of Research (WRAIR) to provide surveillance or research services…
MoreDue Sep 4, 2026Posted Aug 21, 2026 - AN13--Intent to sole source - Miniaturized CO2 Sensor Prototype Development and Novel Physiologic Gas Monitoring ResearchVETERANS AFFAIRS, DEPARTMENT OF / VETERANS AFFAIRS, DEPARTMENT OF
NOTICE OF INTENT TO SOLE SOURCE: IAW FAR 5.101 this notice is to advise the public that The Department of Veterans Affairs RPO-E R&D, intends to award a sole source Firm Fixed Price Contract IAW RFO 6.103-3 and 12.201-1 to the University of Michigan for Miniaturized CO2 Sensor Prototype Development and Novel Physiologic Gas Monitoring Research. THIS NOTICE OF INTENT IS NOT A REQUEST FOR COMPETITIVE PROPOSALS or QUOTATIONS. Responsible sources may identify their interest by submitting…
MoreDue Sep 8, 2026Posted Aug 24, 2026 - Hypobaric Chamber Pilot StudiesNATIONAL AERONAUTICS AND SPACE ADMINISTRATION / NATIONAL AERONAUTICS AND SPACE ADMINISTRATION
This notice is a combined synopsis/solicitation for commercial products and commercial services prepared in accordance with the FAR Part 12, Acquisition of Commercial Products and Commercial Services. This announcement constitutes the only solicitation; offers are being requested and a written solicitation will not be issued. The Government reserves the right to make multiple awards from this RFQ. This notice is being issued as a Request for Quotations (RFQ) under solicitation number…
MoreDue Sep 10, 2026Posted Aug 11, 2026 - Hypoxia Chamber ServicesNATIONAL AERONAUTICS AND SPACE ADMINISTRATION / NATIONAL AERONAUTICS AND SPACE ADMINISTRATION
This notice is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; offers are being requested and a written solicitation will not be issued. The Government reserves the right to make multiple awards form this RFQ. This notice is being issued as a RFQ under solicitation number 80JSC026Q0008 for Hypoxia Chamber…
MoreDue Sep 10, 2026Posted Aug 11, 2026 - Hypobaric Chamber Pilot StudiesNATIONAL AERONAUTICS AND SPACE ADMINISTRATION / NATIONAL AERONAUTICS AND SPACE ADMINISTRATION
This notice is a combined synopsis/solicitation for commercial products and commercial services prepared in accordance with the FAR Part 12, Acquisition of Commercial Products and Commercial Services. This announcement constitutes the only solicitation; offers are being requested and a written solicitation will not be issued. The Government reserves the right to make multiple awards from this RFQ. This notice is being issued as a Request for Quotations (RFQ) under solicitation number…
MoreDue Sep 10, 2026Posted Aug 24, 2026 - Due Sep 11, 2026Posted Aug 25, 2026
- Biological TechnologiesDEPT OF DEFENSE / DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)
The Defense Advanced Research Projects Agency (DARPA) Biological Technologies Office (BTO) is soliciting proposals that leverage biological properties and processes to revolutionize our ability to protect the nation’s warfighters. Specifically excluded is research that primarily results in evolutionary improvements to the existing state of practice.
MoreDue Sep 30, 2026Posted Oct 1, 2025 - TECHNOLOGY LICENSING OPPORTUNITY: Platform to Accelerate Discovery of Tailored Industrial Enzymes (PAD-TIE)ENERGY, DEPARTMENT OF / ENERGY, DEPARTMENT OF
NREL and Los Alamos National Laboratory’s PAD-TIE platform is an advanced screening system designed to accelerate the discovery and optimization of enzymes that break down polyethylene terephthalate (PET), one of the most widely used plastics. The Challenge: Traditional enzyme development is slow and requires testing individual enzymes under controlled conditions. PAD-TIE overcomes this limitation by simultaneously screening tens of thousands of enzyme variants under industrially relevant…
MoreDue Oct 1, 2026Posted Jul 8, 2026
Top awardees
| Awardee | # Awards | Reported Value | Last Award |
|---|---|---|---|
| ALBERT B. SABIN VACCINE INSTITUTE, INC. (THE) UEI H5E8NU6N2HZ5 | 1 | $1B | May 5, 2026 |
| Flosonics Medical LLC Mountain View CA 94040 USA UEI RD81CL8M8EM9 | 1 | $100M | Jun 5, 2026 |
| CHENEGA SERVICES & FEDERAL SOLUTIONS, LLC UEI YN3KSHRHEMM1 | 1 | $72M | May 19, 2026 |
| NATIONAL COLLEGIATE INVENTORS & INNOVATORS ALLIANCE, INC. Hadley MA 01035 USA UEI D5S9JZ1KDP49 | 1 | $1M | Jun 8, 2026 |
| ENGINEERING BIOLOGY RESEARCH CONSORTIUM Emeryville CA 94608 USA UEI M5K1N5ZVSLD5 | 1 | $1M | Jun 8, 2026 |
| ILLUMINA, INC. San Diego CA 92122 USA UEI KMW3CRWNAAF3 | 1 | $273,352 | May 30, 2026 |
| VIRSCIO, INC NEW HAVEN 06511 CTE UEI EYCBWGA47PL5 | 1 | $185,908 | Jun 1, 2026 |
| TWIST BIOSCIENCE CORPORATION San Francisco CA 94080 USA UEI CMN5DM38JLN1 | 1 | $47,450 | Jun 24, 2026 |
Agencies that buy Research and Development in Biotechnology (except Nanobiotechnology)
Related NAICS codes
- 541711 Research and Development in Biotechnology (2012)
- 541712 Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology) (2012)
- 541713 Research and Development in Nanotechnology
- 541715 Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
- 541720 Research and Development in the Social Sciences and Humanities
Frequently asked
Across 16 SAM.gov award notices for NAICS 541714 (Research and Development in Biotechnology (except Nanobiotechnology)), the average reported value is $83M and the median is $1M. SAM.gov award-notice values may represent contract ceilings rather than obligated spending.
8 distinct companies have won awards in NAICS 541714 (Research and Development in Biotechnology (except Nanobiotechnology)).
The agencies awarding the most NAICS 541714 contracts are Dept Of Defense, General Services Administration, Health And Human Services, Department Of.
Yes — 4 of the 38 currently-open Research and Development in Biotechnology (except Nanobiotechnology) opportunities (11%) are set aside for small or disadvantaged businesses.