This notice has been superseded. See the latest notice: ARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions Opening (Solicitation)
SolicitationActiveARPA-H-SOL-26-165
ARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions Opening
HEALTH AND HUMAN SERVICES, DEPARTMENT OF / NATIONAL INSTITUTES OF HEALTH / ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)Key dates?
- Posted?
- Sep 17, 2026
- Response deadline?
- Oct 7, 2026, 6:00 PM UTC
- Archive date?
- Oct 22, 2026
- Archive type?
- auto15
Classification?
- Notice type?
- Solicitation
- Base type?
- Solicitation
- Set-aside?
- —
- Set-aside code?
- —
- PSC?
- AN13
NAICS?
Issuing office?
- Department?
- HEALTH AND HUMAN SERVICES, DEPARTMENT OF
- Sub-tier?
- NATIONAL INSTITUTES OF HEALTH
- Office?
- ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)
- Office code?
- 075.7529.75N992
- Organization type?
- OFFICE
- Office address?
- Washington, DC, 20005, USA
Contacts?
- COSMOS Teamprimary
Description?
The Advanced Research Projects Agency for Health (ARPA-H) Comprehensive Organ System Modeling in Outer Space (COSMOS) Initiative aims to definitively prove or disprove if exposure to microgravity in Low Earth Orbit (LEO) truly accelerates tissue aging across brain, cardiac, uterine, and kidney tissue types and across several adult age brackets. Provided Tissue Aging Rate in Space (TARIS) exceeds Tissue Aging Rate on Earth (TAROE) at a rate that exceeds the on Earth breakeven cost for new drug R&D, COSMOS will create a first-in-class platform for fully autonomous, high-throughput drug screening in LEO that would be more cost effective and faster than new drug R&D on Earth. ARPA-H anticipates multiple Other Transaction awards resulting from this announcement. Interested parties are invited to download and review the attached COSMOS Innovative Solutions Opening (ISO) ARPA-H-SOL-26-165 Amendment 01 – 17 September 2026: This amendment includes updated hyperlinks and information on the updated Solutions summary portal.
Attachments (8)?
- Download📎 ATTACHMENT+B_COSMOS+Eligibility+and+Conformance+Certification+Sheet.docxapplication/octet-stream · 36 KB
- Download📎 Attachment+D_COSMOS+Cost+Proposal+Template.xlsxapplication/octet-stream · 146 KB
- Download📎 Attachment+E_COSMOS+Administrative+and+National+Policy+Requirements.docxapplication/octet-stream · 95 KB
- Download📎 ATTACHMENT+A.2_Task+Description+Document+Model.docxapplication/octet-stream · 42 KB
- Download📎 ARPA-H-SOL-26-165_COSMOS_ISO_Amendment+01.pdfapplication/pdf · 1.8 MB
- Download📎 ATTACHMENT+C+COSMOS+Schedule.xlsxapplication/octet-stream · 20 KB
- Download📎 ATTACHMENT+A.1_Technical+%26+Management+Proposal+Model+%28VOL+I%29.docxapplication/octet-stream · 55 KB
- Download📎 ATTACHMENT+A.3_COSMOS+Milestone+and+Payment+Table.xlsxapplication/octet-stream · 22 KB
Other notices in this solicitation?
- SolicitationARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions OpeningOct 7, 2026LATEST
- SolicitationARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions OpeningSep 25, 2026
- SolicitationARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions OpeningSep 23, 2026
- SolicitationARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions OpeningSep 21, 2026
- SolicitationARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions OpeningSep 16, 2026
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Metadata?
- Notice ID?
- a0daed815bbc41289b0477bf9520ab1b
- Full path?
- HEALTH AND HUMAN SERVICES, DEPARTMENT OF.NATIONAL INSTITUTES OF HEALTH.ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)
- Office code?
- 075.7529.75N992
- Ingested?
- Sep 18, 2026
- Updated?
- Sep 29, 2026