US-FED-00000390122 - Office on Women`s Health for Midlife through Menopause Mortality and Morbidity Reduction Initiative - Deadline August 17,2026

Purpose of NoticeThe U.S. Department of Health and Human Services (DHHS), Office of Mission Acquisition Solutions (OMAS), Office on Women`s Health (OWH), seeks to identify qualified organizations capable of accessing a national inpatient and outpatient database to conduct ongoing longitudinal statistical analyses and to establish and manage healthcare–related quality improvement learning collaboratives to support measurement of the impact of evidence–based interventions on outcomes for midlife and menopausal women.This Sources Sought Notice is intended to assess the availability and interest of potential small businesses with expertise in women`s health, data analysis, clinical implementation, health systems engagement, development and implementation of large quality improvement collaboratives, and evaluation of interventions involving breast cancer screening and reduction of UTI–related outcomes through vaginal estrogen therapy. This work requires access to large, nationally representative inpatient and outpatient data sets.This is a Small Business Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources; (2) whether they are small businesses; HUBZone small businesses; service–disabled, veteran–owned small businesses; 8(a) small businesses; veteran–owned small businesses; woman–owned small businesses; or small disadvantaged businesses; and (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set–aside is possible. An organization that is not considered a small business under the applicable NAICS code should not submit a response to this notice.The purpose of this Sources Sought Notice is to identify capable sources and obtain industry input on the feasibility, scope, sequencing, data requirements, implementation approach, risks, and acquisition structure for the contemplated initiative.The aim of this initiative is to promote healthy aging and wellness and to reduce morbidity and mortality among midlife and menopausal women by strengthening breast cancer screening and early detection and preventing complications associated with recurrent urinary tract infections.Responses should help HHS determine:Whether capable small business sources exist for the combined requirement, for either workstream separately, or for defined portions of a workstream.The availability, validity, timeliness, and licensing constraints of national or nationally generalizable inpatient and outpatient data needed for the contemplated analyses.Whether available data can validly identify the midlife and menopausal target population, breast screening modality and purpose, recurrent UTI, clinically appropriate vaginal estrogen use, sepsis, hospitalization, and mortality.The feasible size, composition, recruitment timeline, data burden, and operating model for the contemplated health care quality improvement learning collaboratives.Appropriate contract structure, period of performance, contract type, contract vehicle, data licensing model, and Government–furnished resources.Potential barriers to competition, including data ownership, licensing restrictions, proprietary analytic platforms, conflicts of interest, site recruitment dependencies, and specialized clinical expertise.The following section describes the program objectives and scope for which HHS seeks industry feedback.PROGRAM OVERVIEWThe contemplated initiative would integrate national longitudinal data analysis with multi–site quality–improvement learning collaboratives to strengthen evidence–based care and improve outcomes for women in midlife and through the menopausal transition. HHS is considering two distinct workstreams:Workstream 1 – Breast Cancer Screening and Diagnostic Follow–up: improve appropriate screening, access, modality selection, follow–up after abnormal findings, diagnostic resolution, and early cancer identification.Workstream 2 – Recurrent Urinary Tract Infection (UTI) and Severe Outcome Reduction: improve evidence–based prevention and management of recurrent UTI, including appropriate use of vaginal estrogen among clinically eligible peri– and postmenopausal patients, and evaluate recurrent infection, acute care use, sepsis, hospitalization, and mortality.The final scope, sequence, measures, data requirements, and acquisition structure may be refined based on market research responses.BACKGROUND