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Cap-dependent endonuclease inhibitors (CENis) - NHRC

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Key dates

Posted
May 15, 2026
Response deadline
May 25, 2026, 9:00 PM UTC
Archive date
—
Archive type
auto15

Classification

Notice type
Combined Synopsis/Solicitation
Base type
Combined Synopsis/Solicitation
Set-aside
No Set aside used
Set-aside code
NONE
PSC
AN42

NAICS

Issuing office

Department
DEPT OF DEFENSE
Sub-tier
DEPT OF THE NAVY
Office
NAVSUP FLT LOG CTR NORFOLK
Office code
017.1700.NAVSUP.NAVSUP GLS.NAVSUP FLC NORFOLK.N00189
Organization type
OFFICE
Office address
NORFOLK, VA, 23511-3392, USA

Place of performance

Street
—
Street 2
—
City
Galveston
State
Texas
Zip
—
Country
UNITED STATES

Contacts

Description

The preclinical development of Cap-dependent endonuclease inhibitors (CENi), a class of small molecules, as broad-spectrum antiviral therapeutics. The scope of this project includes all activities required to select lead CENi candidates, including in vitro and in vivo efficacy studies and characterization and optimization of lead compounds. This includes Research Support expertise regarding the preclinical development of cap-dependent endonuclease inhibitors (CENis) with viruses that require biosafety level 4 (BSL-4) containment to support the Naval Medical Research Command in Fort Detrick, MD. This work will be performed over a 36-month period.

Attachments (3)

Other notices in this solicitation

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Metadata

Notice ID
7ca6661dd9ec4edb86296ad3bc28a805
Full path
DEPT OF DEFENSE.DEPT OF THE NAVY.NAVSUP FLT LOG CTR NORFOLK
Office code
017.1700.NAVSUP.NAVSUP GLS.NAVSUP FLC NORFOLK.N00189
Ingested
May 16, 2026
Updated
Jun 12, 2026